Kidney Lymphoma and the Importance of Computed Tomography (CT)

Published: 17th December 2008
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Kidney lymphoma is most frequently observed along with multisystemic, dispersed lymphoma or as tumor reappearance. Kidney lymphoma might be observed in immunocompromised patients or, hardly ever, as primary disease as well.

With the kidneys being the most usually involved organs, extranodal spread of lymphoma frequently influences the genitourinary system.

The lymphoma can obstruct urine from leaving the kidney. This could cause kidney failure, which could lead to low urine output, weariness, loss of appetite, nausea, or swelling in the hands or feet. The lymphoma could obstruct feces as well moving by means of the bowel. This bowel stumbling block could lead to nausea, vomiting, and serious abdominal pain.

Lymphoma of the kidneys is detected at the time of autopsy in nearly one half of cases. It is seldom suspected on conventional urologic surveys like intravenous urography.

In the nonattendance of right clinical treatment, since involvement of the kidneys typically points to dispersed disease the prognosis is poor. The disease can present with progressive kidney failure. Survival is really poor in principal kidney lymphoma: in less than 1 year75% of patients die. By early detection of the disease and by doing systemic chemotherapy the prognosis could be recovered.

Kidney lymphoma displays no racial predilection. Kidney lymphoma shows no sex predilection. Nonetheless, it is allegedly perceived more frequently in male patients. Kidney lymphoma takes place in every age group. The disease typically influences adults; but, kidney lymphoma has been reported in childhood as well.

For the detection, diagnosis, staging, and monitoring of kidney lymphoma, contrast material-enhanced computed tomography (CT) remains the modality of option. In patients in whom intravenous administration of iodinated contrast material is contraindicated, magnetic resonance (MR) imaging is principally helpful. Ultrasonography (US) is less sensitive than CT and MR imaging for identifying kidney lymphoma, though really useful for diagnosing lymphoma in the testis or epididymis.

However, in patients with suspected kidney lymphoma, the most sensitive, efficient, and complete examination for evaluation of the kidneys is computed tomography (CT). Helical CT especially recovers detection and characterization of lymphomatous kidney involvement by optimizing contrast dynamics and data acquisition. It is the present modality of option for precise staging of lymphoma.

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